TIM3 expression by leukemic and non-leukemic myeloblasts
نویسندگان
چکیده
منابع مشابه
Glycosaminoglycans in Human Neutrophils and Leukemic Myeloblasts : Ultrastructural ,
Chondroitin sulfate is known to be present in normal and leukemic myeloid cells; however. its definitive subcellular location and association with other glycosaminoglycans (GAGs) has not been demonstrated. We have studied the type and distribution of GAGs in neutrophil granule subpopulations of normal and leukemic myeloid cells using ultrastructural. cytochemical. immunologic. and biochemical m...
متن کاملUltrastructure and Cytokinetics of Leukemic Myeloblasts Containing Giant Granules1
Leukemic myeloblasts containing abnormal granules were studied with ultrastructural, cytochemical, and thymidine label ing techniques to evaluate defects in granulogenesis and pro liferation. Giant granules (1 to 3 /im in diameter) and Auer rods were observed in leukemic cells from two patients, and only rarely were both abnormal granule types observed in the same cell. The lysosomal origin of ...
متن کاملUltrastructure and cytokinetics of leukemic myeloblasts containing giant granules.
Leukemic myeloblasts containing abnormal granules were studied with ultrastructural, cytochemical, and thymidine labeling techniques to evaluate defects in granulogenesis and proliferation. Giant granules (1 to 3 micron in diameter) and Auer rods were observed in leukemic cells from two patients, and only rarely were both abnormal granule types observed in the same cell. The lysosomal origin of...
متن کاملSerologic characterization of a monkey antiserum to human leukemic myeloblasts.
We have raised a monkey antiserum that is selectively reactive with human leukemic myeloblasts by immunization with a glycoprotein antigen (AMLSGA) released from myeloblasts in short-term culture. Antimyeloblast activity can be demonstrated using complement-dependent cytotoxicity or indirect immunofluorescence. Selective antimyeloblast activity is retained following absorption with leukemic lym...
متن کاملEndothelial cell activation by myeloblasts: molecular mechanisms of leukostasis and leukemic cell dissemination.
Leukostasis and tissue infiltration by leukemic cells are poorly understood life-threatening complications of acute leukemia. This study has tested the hypothesis that adhesion receptors and cytokines secreted by blast cells play central roles in these reactions. Immunophenotypic studies showed that acute myeloid leukemia (AML) cells (n = 78) of the M0 to M5 subtypes of the French-American-Brit...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cytometry Part B: Clinical Cytometry
سال: 2013
ISSN: 1552-4949
DOI: 10.1002/cyto.b.21080